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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
6.67
Human Site:
S22
Identified Species:
11.28
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S22
G
P
A
S
F
K
F
S
G
V
C
P
D
S
R
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S22
G
S
A
S
F
K
L
S
G
V
C
P
D
S
R
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
I22
F
P
F
T
P
Y
S
I
Q
E
D
F
M
A
E
Dog
Lupus familis
XP_543872
907
102087
I22
F
P
F
T
P
Y
S
I
Q
K
D
F
M
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
D25
P
P
Y
P
I
Q
K
D
F
M
A
E
L
Y
K
Rat
Rattus norvegicus
XP_001070646
845
94905
K24
F
P
P
Y
P
I
Q
K
D
F
M
A
E
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
C22
E
R
A
R
A
R
L
C
V
T
R
Q
E
R
M
Chicken
Gallus gallus
XP_416375
940
105739
V27
A
V
G
G
S
G
R
V
L
P
D
A
C
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
V34
T
A
L
D
Q
R
K
V
G
I
F
E
S
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
S23
Q
E
F
G
F
P
Y
S
P
Y
E
I
Q
E
Q
Honey Bee
Apis mellifera
XP_001121183
769
88327
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
Q22
K
P
Y
D
I
Q
V
Q
L
M
E
T
V
Y
R
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
T98
N
P
S
T
S
P
S
T
P
P
L
I
N
P
T
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
86.6
6.6
6.6
N.A.
6.6
6.6
N.A.
6.6
13.3
N.A.
6.6
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
86.6
20
20
N.A.
26.6
13.3
N.A.
20
13.3
N.A.
20
N.A.
26.6
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
22
0
8
0
0
0
0
0
8
15
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
15
0
8
0
0
% C
% Asp:
0
0
0
15
0
0
0
8
8
0
22
0
15
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
8
15
15
15
8
15
% E
% Phe:
22
0
22
0
22
0
8
0
8
8
8
15
0
0
0
% F
% Gly:
15
0
8
15
0
8
0
0
22
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
8
0
15
0
8
0
15
0
0
0
% I
% Lys:
8
0
0
0
0
15
15
8
0
8
0
0
0
0
8
% K
% Leu:
0
0
8
0
0
0
15
0
15
0
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
15
8
0
15
0
8
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
50
8
8
22
15
0
0
15
15
0
15
0
15
0
% P
% Gln:
8
0
0
0
8
15
8
8
15
0
0
8
8
0
8
% Q
% Arg:
0
8
0
8
0
15
8
0
0
0
8
0
0
8
29
% R
% Ser:
0
8
8
15
15
0
22
22
0
0
0
0
8
22
0
% S
% Thr:
8
0
0
22
0
0
0
8
0
8
0
8
0
0
15
% T
% Val:
0
8
0
0
0
0
8
15
8
15
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
8
0
15
8
0
0
8
0
0
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _